Jena University Hospital, Germany

The Jena university hospital (JUH) includes 26 clinical centers and 25 institutes and provides care for 53,000 in- and 275,000 outpatients per year, as well as teaching for 2,500 students of medicine, molecular medicine and medical photonics. The “Center for Sepsis Control & Care” of the Jena University addresses sepsis research covering all aspects of the disease and its sequelae. It belongs to the world leading institutions in sepsis research and is embedded in a variety of national and international research networks focusing on infections and intensive care medicine. The CSCC successfully develops and implements advanced microphysiological systems emulating the human lung, liver and gut and related disease models in basic research and translational medicine. The CSCC thereby offers a unique interdisciplinary research environment at the interface of physics, biomaterials, immunology, medicine and microbiology aiming on the development of novel treatment options for critically ill patients.

Role in the project:

• Chair of scientific board
• PI: development of liver-on-chip with metabolic patterning
• PI: development of gut-on-chip stably colonized with synthetic commensal microbial communities, models of dysbiosis
• PI: development of immunocompetent organ models based on hiPSC