ESR 11

Name: Aina Kehinde Oluwasegun

Host Organisation: Jena University Hospital

Project Title: Establishment of a liver zonation and infection model

Objectives of the Project

  1. To establish bioengineered hiPSC derived human liver-on-chip models;
  2. To develop a microfluidic platform with non-invasive sensor readout technologies for metabolic analysis of liver function;
  3. To establish metabolic patterning of hepatocytes and non-parenchymal cells as complex in vitro model for drug testing and disease modeling.
  4. To form multi systems by integrating the WAT model with the Liver on chip.

Secondments

  • Universite du Luxembourg, Luxembourg for 2 months;
  • Technical University Graz, Austria for 2 months;
  • Boehringer Ingelheim Pharma GmbH & Co. KG

Short Biography

Kenny is a PhD student and holds a B.Sc. in Microbiology and M.Sc. in Medical Microbiology and Parasitology. He is Early Stage Researcher in the Innovative Training Network EUROoC and develops a hiPSC based liver-on-chip model. His work focuses on metabolic pattern of liver zonation and disease mechanisms of non-alcoholic steatohepatitis.

Research interests: hiPSC hepatocyte biology, NASH, Gut-liver axis

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